Pensum: 100%
PhD Position (Translational Tumor Immunology)
Aufgaben
- Investigate mechanisms of response and resistance to immune checkpoint blockade in solid tumors, with a focus on head and neck and esophagogastric cancers
- Characterize the tumor immune microenvironment using spatial proteomics, multiplex imaging and spatial transcriptomics
- Integrate tissue-based immune profiles with blood-based biomarkers, immune repertoires and clinical outcomes to identify markers for patient stratification and treatment response
- Establish patient-derived 3D tumor models and explants and perform functional tumor–immune cell experiments to validate resistance mechanisms and therapeutic strategies
- Take an active role in planning and conducting the project, analysing complex datasets, collaborating with clinical and scientific partners, and presenting and publishing your findings
Profil
- Master's degree in biology, biomedical sciences, biochemistry, molecular medicine, immunology, cancer biology or a related life-science discipline
- Strong interest in translational cancer research, tumor immunology and modern spatial profiling technologies
- Solid hands-on experience in mammalian cell culture and molecular or cellular biology, ideally in the context of tumor biology
- Initiative, scientific curiosity and the ability to work independently and collaboratively in an interdisciplinary and international environment
- Excellent English language skills; experience with primary human samples, flow cytometry, spatial technologies, 3D models, functional assays or quantitative data analysis using R/Python is an advantage
Angebot
- Attraktive Lohnpolitik und hervorragende Sozialleistungen
- Vergünstigungen in den Bereichen Shopping, Sport und Freizeit
- Unterstützung bei Umzug und Wohnungssuche
- 25 Ferientage plus 5 ebenfalls freie Flexitage
- Unterstützung bei Fort- und Weiterbildungen und Karriereplanung
- Campus im Herzen Basels und im Dreiländereck
- Umfassende Kinderbetreuungsmöglichkeiten
- Kostenloses Sport- und Bewegungsprogramm
Quelle: Arbeitgeber-Karriereseite. Zuletzt automatisch geprüft am 2026-10-16. Bewerbung erfolgt direkt beim Arbeitgeber.
